【Abstract】 Objective To study the difference of Hantavirus genotype among rats at Changchun Longjia international airport. Methods From Apr. 2006 to Mar. 2007, rodents were captured by snap trap (mouse clamp). Samples were detected by direct immunofluorescence technique. The partial M fragments were amplified with nested reverse transcription polymerase chain reaction (RT-PCR) using Hantavirus genotype-specific primers, and its sequence was analyzed. Results There were 195 mice captured, and about 10 mice took the Hantavirus. There were 4 Hantaan viruses and 6 Seoul viruses. Nucleotide sequence homology analysis showed that there was some mutation in the Hantavirus and no found new sub-genotype. Conclusion There are Hantaan viruses and Seoul viruses at Changchun Longjia international airport, which is valuable for the prevention and control of hemorrhagic fever with renal syndrome.